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    In organic synthesis, glacial acetic acid often acts as a solvent or reagent. Its relatively high pKa means it can serve as a proton donor in reactions where stronger acids would be overly aggressive. This property is especially beneficial in processes such as esterification, where acetic acid reacts with alcohols to form esters and water. Here, the pKa influences the reaction's equilibrium, affecting the yield of the ester product.


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  • Understanding Glacial Acetic Acid and Its Properties in Various Applications

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